date:Nov 06, 2012
Register by Commission Decision 2008
In experiments on animals 2-Methylbuta-1,3-diene showed genotoxic potential and carcinogenic effects in experimental animals and it was concluded it could be possibly carcinogenic to humans, according to an EC report.
A statement from the EC said: Methylbuta-1,3-diene is clearly carcinogenic in both mice and rats, and although the mechanism of tumour formation is unknown, the possibility of a genotoxic mechanism can not be discounted. The JECFA considered i