Fructose, Sucrose Alter Hepatic Insulin Sensitivity
date:Sep 12, 2012
ouble-blind, randomized, cross-over trial. All subjects consumed four different beverages (600 mL/day) sweetened with medium or high fructose, high glucose, or high sucrose for three weeks each.

Hepatic suppression of glucose production during the clamp was significantly lower after high fructose (59.4 11.0%) than high glucose (70.3 10.5%, P 0.05), whereas fasting glucose, insulin, and C-peptide did not differ between the interventions. Low-density lipoprotein cholesterol and total cholester
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