date:Feb 25, 2019
l studies have shown that urea A, a microbial metabolite extracted from berries and pomegranates, and its newly synthesized analogues can effectively alleviate the symptoms of acute and chronic colitis. After completing many experiments in vitro and in vivo, the researchers found that small molecules such as urea A can increase the content of many key proteins in intestinal tract, enhance the connection between intestinal mucosal epithelial cells, stabilize intestinal barrier, then reduce intest