EFSA rejects Merck glucosamine-joint health appeal
date:Aug 17, 2012
ynovial fluid, the Panel considered that uptake of glucosamine into cartilage cells would be very limited underin vivoconditions.

It saidin vitroand animal studies showing joint health mechanisms wasweak,and not necessarily able to,predict an effect of glucosamine on joint cartilage in humans.

Urinary concentrations of type II collagen fragments were not valid biomarkers to predict joint cartilage degradation.

On study group extrapolation it affirmed,no conclusions could be drawn from the stu
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