date:Jun 21, 2016
r shortages. Saccharin has a long history of safe use by humans; however, a series of experiments in the 1970s showed that consumption of large amounts caused bladder cancer in male rats. As a result, saccharin was banned in some countries (e.g., Canada) and required a warning label in the United States. In 2000, these safety decisions were reversed when scientists determined that the mechanism for bladder tumor formation in the male rats did not occur in humans. Consequently, products that cont