date:Jul 31, 2015
issue in the Journal of Lipid Research, questions the relevance of fish oil-derived SPMs and their purported anti-inflammatory effects in humans.
Getting clarity on the true benefit of fish oils first requires some elementary chemistry: When humans eat fish, we consume omega-3 polyunsaturated fatty acids in triglyceride form (the source of SPMs), which are bound to a glycerol backbone. This is how fatty acids are stored in nature since free fatty acids oxidize quickly. To make fish oil supplem