EFSA presents cumulative assessment group methodology for pesticides
date:Jul 15, 2013
3. Data collection gathering data on the indicators (e.g. changes in hormone levels at the dose where the advesre effect occurs) that point to a specific toxic effect (e.g. imbalance of the thyroid system) in an organ/system.

4. Grouping of pesticides that exhibit a similar toxicological effect into cumulative assessment groups by organ or system (e.g. thyroid).

This approach requires expert scientific judgment as it involves the analysis and interpretation of large volumes of complex data. I
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