date:Apr 16, 2013
probiotics.
Maintaining healthy microbiota requires action by nucleotide-binding oligomerization domain protein-like receptors, pyrin-domain containing (NLRP)-6 inflammasomes.
However, when stressed, mice produced corticotropin-releasing hormone (CRH) that prevented inflammasomes from doing their job.
Inhibiting inflammosomes alters the composition of the gut, leading to intestinal inflammation. In the study, pretreatment with probiotic therapy reduced inflammation in mice with stress-induce