date:Mar 12, 2013
A is attached to the cell's androgen receptor. When androgen levels drop, some prostate cancer cells eject the filamin A, which frees the cancer cell from its dependence on male sex hormones and makes it resistant to hormone deprivation treatment and therefore essentially incurable.
In the new study, conducted in both mice and in human prostate cancer cells, the researchers found that a natural mushroom-soybean extract called genistein-combined polysaccharide (GCP) actually prevents prostate ca