date:Aug 24, 2018
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To adapt phages bacteria-killing abilities for bacteria detection, the researchers inserted the gene for a reporter enzyme into a bacteriophage called T7NLC. The reporter enzyme, a luciferase known as NanoLuc, glows when expressed by bacterial cells, thus detecting E. coli. Fused to the enzyme is a module that binds to cellulose to provide a way to collect the enzymes for analysis.
When researchers added the engineered bacteriophages to E. coli contaminated water along with ins